{"id":46803,"date":"2026-09-18T03:47:03","date_gmt":"2026-09-18T00:47:03","guid":{"rendered":"https:\/\/kuzeyinsesi.org\/index.php\/2026\/09\/18\/bilimsel-bir-atilimla-yari-insan-yari-fare-beyin-gelistirildi\/"},"modified":"2026-09-18T03:47:03","modified_gmt":"2026-09-18T00:47:03","slug":"bilimsel-bir-atilimla-yari-insan-yari-fare-beyin-gelistirildi","status":"publish","type":"post","link":"https:\/\/kuzeyinsesi.org\/index.php\/2026\/09\/18\/bilimsel-bir-atilimla-yari-insan-yari-fare-beyin-gelistirildi\/","title":{"rendered":"Bilimsel bir at\u0131l\u0131mla yar\u0131 insan yar\u0131 fare beyin geli\u015ftirildi"},"content":{"rendered":"

<\/p>\n

\n


\n\tBeyinlerinin bir k\u0131sm\u0131 insan olan fareler Kafka tarz\u0131 bir deneyi \u00e7a\u011fr\u0131\u015ft\u0131rabilse de bilim insanlar\u0131 bunlar\u0131n “insan gibi d\u00fc\u015f\u00fcnen fareler” olmad\u0131\u011f\u0131n\u0131 belirtti.<\/p>\n


\n\tHayvanlar, beyin dokular\u0131n\u0131n bir k\u0131sm\u0131n\u0131n insan olaca\u011f\u0131 \u015fekilde genetik<\/a> olarak m\u00fchendislikle geli\u015ftirildi ve cerrahi olarak de\u011fi\u015ftirildi.<\/p>\n


\n\tBilim insanlar\u0131 Nature dergisinde yay\u0131nlanan \u00e7al\u0131\u015fmalar\u0131n\u0131n ba\u011f\u0131ms\u0131z etik denetimler e\u015fli\u011finde y\u00fcr\u00fct\u00fcld\u00fc\u011f\u00fcn\u00fc ifade etti.<\/p>\n


\n\tTedavisi olmayan beyin bozukluklar\u0131 incelenecek<\/h2>\n


\n\tAra\u015ft\u0131rmac\u0131lar, implante edilen farelerin taramalar\u0131nda insan beyin h\u00fccreleri ile fare beyininin geri kalan\u0131 aras\u0131ndaki ba\u011flant\u0131lar\u0131 g\u00f6rebildi.<\/p>\n


\n\tEtik a\u00e7\u0131dan karma\u015f\u0131k olan bu at\u0131l\u0131m\u0131n amac\u0131, hen\u00fcz etkili tedavileri bulunmayan beyin bozukluklar\u0131n\u0131n biyolojisini daha iyi anlamak.<\/p>\n


\n\tBaz\u0131 durumlar kemirgenlerde bu rahats\u0131zl\u0131klar geli\u015fmedi\u011fi i\u00e7in fareler \u00fczerinde incelenemiyor.<\/p>\n


\n\tStanford \u00dcniversitesi’nden ba\u015f ara\u015ft\u0131rmac\u0131 Prof. Sergiu Pa\u015fca’n\u0131n bir bas\u0131n toplant\u0131s\u0131nda a\u00e7\u0131klad\u0131\u011f\u0131 \u00fczere, psikiyatri<\/a> “klinik ara\u015ft\u0131rmalar i\u00e7in en d\u00fc\u015f\u00fck ba\u015far\u0131 oranlar\u0131ndan birine” sahip.<\/p>\n


\n\tPa\u015fca bas\u0131n toplant\u0131s\u0131nda, “Klinik a\u015famaya kadar gelen ve hayvan modellerinde ger\u00e7ekten \u00e7ok iyi \u00e7al\u0131\u015ft\u0131\u011f\u0131 g\u00f6r\u00fclen ila\u00e7lar bile klinikte dramatik bir \u015fekilde ba\u015far\u0131s\u0131z oluyor.” dedi ve ekledi: “Bu bize insan biyolojisi hakk\u0131nda \u00e7ok fazla bilgiyi ka\u00e7\u0131rd\u0131\u011f\u0131m\u0131z\u0131 s\u00f6yl\u00fcyor ve bunu yakalamak \u00e7ok \u00f6nemli olacak.”<\/p>\n


\n\tStanford ara\u015ft\u0131rmac\u0131lar\u0131, epilepsi, otizm<\/a> ve serebral palsi dahil olmak \u00fczere baz\u0131 karma\u015f\u0131k durumlar i\u00e7in bunun “d\u00f6n\u00fc\u015ft\u00fcr\u00fcc\u00fc” olma potansiyeline sahip oldu\u011funu belirtti.<\/p>\n


\n\tPa\u015fca, “Burada, insan beyin fonksiyonlar\u0131n\u0131n baz\u0131 y\u00f6nlerini daha \u00f6nce m\u00fcmk\u00fcn olmayan bir \u015fekilde yakalamam\u0131za olanak tan\u0131yan yeni bir modelimiz var.” dedi.<\/p>\n


\n\t‘Gri maddesi’ olmayan fareler<\/h2>\n


\n\t\u0130nsan beyni, milyarlarca h\u00fccreden ve milyonlarca devre halinde birbirine ba\u011flanm\u0131\u015f yap\u0131lardan olu\u015fuyor; bu durum, geli\u015fimi ve i\u015fler ters gitti\u011finde h\u00fccresel d\u00fczeyde tam olarak ne oldu\u011funu anlamay\u0131 zorla\u015ft\u0131r\u0131yor.<\/p>\n


\n\tBu ara\u015ft\u0131rma, insan n\u00f6ronlar\u0131n\u0131n laboratuvar kemirgenlerine ilk kez implante edildi\u011fi \u00e7al\u0131\u015fma olmasa da bu bilim insanlar\u0131 bu yakla\u015f\u0131m\u0131 bir \u00fcst seviyeye ta\u015f\u0131d\u0131.<\/p>\n


\n\t\u0130lk olarak bilim insanlar\u0131, kendi serebral kortekslerinin -yani “gri madde” olarak da adland\u0131r\u0131lan beynin d\u0131\u015f tabakas\u0131n\u0131n- neredeyse hi\u00e7birini geli\u015ftirmeyecek \u015fekilde fareleri genetik olarak tasarlad\u0131.<\/p>\n


\n\tKorteks, \u00fcst d\u00fczey d\u00fc\u015f\u00fcnme, haf\u0131za ve duyular\u0131 y\u00f6netiyor.<\/p>\n


\n\tAra\u015ft\u0131rmac\u0131lar daha sonra insanlardan al\u0131nan deri h\u00fccrelerini “yeniden programlayarak” beyin benzeri doku par\u00e7alar\u0131na d\u00f6n\u00fc\u015fmelerini sa\u011flad\u0131.<\/p>\n


\n\tOrganoit ad\u0131 verilen bu yap\u0131lar, petri kaplar\u0131nda yeti\u015ftirilmi\u015f b\u00fct\u00fcn beyinler de\u011fil, daha ziyade birbirine ba\u011fl\u0131 ya\u015fayan h\u00fccre topluluklar\u0131.<\/p>\n


\n\tBu organoitler fare beynine implante edildi\u011finde h\u00fccreler b\u00f6l\u00fcnd\u00fc ve hayvan\u0131n mevcut beyin devresi i\u00e7inde organize olarak farenin beyninin geri kalan\u0131 ve omurili\u011fi ile ba\u011flant\u0131 kurdu.<\/p>\n


\n\t\u0130mplante edilen farelerin korteksi m\u00fckemmel de\u011fil; normal korteks organize, yap\u0131land\u0131r\u0131lm\u0131\u015f katmanlar olu\u015fturuyor. N\u00f6robilimci Dr. Ilary Allodi’nin belirtti\u011fi gibi, bu insan-fare beyinlerinin taramalar\u0131 “biraz da\u011f\u0131n\u0131k” g\u00f6r\u00fcn\u00fcyor.<\/p>\n


\n\tAncak birka\u00e7 ay sonra insan h\u00fccreleri, farenin beyninin d\u0131\u015f tabakas\u0131 gibi g\u00f6r\u00fcnmeye ve i\u015flev g\u00f6rmeye ba\u015flad\u0131.<\/p>\n


\n\tAmeliyattan yakla\u015f\u0131k alt\u0131 ay sonra bilim insanlar\u0131 fareleri k\u00fc\u00e7\u00fck bir masa \u00fcst\u00fc arenada hareket ederken g\u00f6zlemleyerek baz\u0131 temel davran\u0131\u015f testlerine tabi tuttu.<\/p>\n


\n\tPa\u015fca, farelerin “[normal] farelerin yapt\u0131\u011f\u0131 gibi b\u00fcy\u00fck \u00f6l\u00e7\u00fcde” performans g\u00f6sterdi\u011fini s\u00f6yledi.<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

Beyinlerinin bir k\u0131sm\u0131 insan olan fareler Kafka tarz\u0131 bir deneyi \u00e7a\u011fr\u0131\u015ft\u0131rabilse de bilim insanlar\u0131 bunlar\u0131n “insan gibi d\u00fc\u015f\u00fcnen fareler” olmad\u0131\u011f\u0131n\u0131 belirtti. Hayvanlar, beyin dokular\u0131n\u0131n bir k\u0131sm\u0131n\u0131n insan olaca\u011f\u0131 \u015fekilde genetik olarak m\u00fchendislikle geli\u015ftirildi ve cerrahi olarak de\u011fi\u015ftirildi. Bilim insanlar\u0131 Nature dergisinde yay\u0131nlanan \u00e7al\u0131\u015fmalar\u0131n\u0131n ba\u011f\u0131ms\u0131z etik denetimler e\u015fli\u011finde y\u00fcr\u00fct\u00fcld\u00fc\u011f\u00fcn\u00fc ifade etti. Tedavisi […]<\/p>\n","protected":false},"author":1,"featured_media":46804,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jnews-multi-image_gallery":[],"jnews_single_post":[],"jnews_primary_category":[],"jnews_social_meta":[],"jnews_override_counter":[],"footnotes":""},"categories":[2],"tags":[],"class_list":["post-46803","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dunya"],"yoast_head":"\nBilimsel bir at\u0131l\u0131mla yar\u0131 insan yar\u0131 fare beyin geli\u015ftirildi - Kuzeyin Sesi<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/kuzeyinsesi.org\/index.php\/2026\/09\/18\/bilimsel-bir-atilimla-yari-insan-yari-fare-beyin-gelistirildi\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bilimsel bir at\u0131l\u0131mla yar\u0131 insan yar\u0131 fare beyin geli\u015ftirildi - Kuzeyin Sesi\" \/>\n<meta property=\"og:description\" content=\" Beyinlerinin bir k\u0131sm\u0131 insan olan fareler Kafka tarz\u0131 bir deneyi \u00e7a\u011fr\u0131\u015ft\u0131rabilse de bilim insanlar\u0131 bunlar\u0131n “insan gibi d\u00fc\u015f\u00fcnen fareler” olmad\u0131\u011f\u0131n\u0131 belirtti. Hayvanlar, beyin dokular\u0131n\u0131n bir k\u0131sm\u0131n\u0131n insan olaca\u011f\u0131 \u015fekilde genetik olarak m\u00fchendislikle geli\u015ftirildi ve cerrahi olarak de\u011fi\u015ftirildi. Bilim insanlar\u0131 Nature dergisinde yay\u0131nlanan \u00e7al\u0131\u015fmalar\u0131n\u0131n ba\u011f\u0131ms\u0131z etik denetimler e\u015fli\u011finde y\u00fcr\u00fct\u00fcld\u00fc\u011f\u00fcn\u00fc ifade etti. 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Kuzeyin Sesi","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/kuzeyinsesi.org\/index.php\/2026\/09\/18\/bilimsel-bir-atilimla-yari-insan-yari-fare-beyin-gelistirildi\/","og_locale":"tr_TR","og_type":"article","og_title":"Bilimsel bir at\u0131l\u0131mla yar\u0131 insan yar\u0131 fare beyin geli\u015ftirildi - Kuzeyin Sesi","og_description":" Beyinlerinin bir k\u0131sm\u0131 insan olan fareler Kafka tarz\u0131 bir deneyi \u00e7a\u011fr\u0131\u015ft\u0131rabilse de bilim insanlar\u0131 bunlar\u0131n “insan gibi d\u00fc\u015f\u00fcnen fareler” olmad\u0131\u011f\u0131n\u0131 belirtti. Hayvanlar, beyin dokular\u0131n\u0131n bir k\u0131sm\u0131n\u0131n insan olaca\u011f\u0131 \u015fekilde genetik olarak m\u00fchendislikle geli\u015ftirildi ve cerrahi olarak de\u011fi\u015ftirildi. Bilim insanlar\u0131 Nature dergisinde yay\u0131nlanan \u00e7al\u0131\u015fmalar\u0131n\u0131n ba\u011f\u0131ms\u0131z etik denetimler e\u015fli\u011finde y\u00fcr\u00fct\u00fcld\u00fc\u011f\u00fcn\u00fc ifade etti. Tedavisi […]","og_url":"https:\/\/kuzeyinsesi.org\/index.php\/2026\/09\/18\/bilimsel-bir-atilimla-yari-insan-yari-fare-beyin-gelistirildi\/","og_site_name":"Kuzeyin Sesi","article_publisher":"https:\/\/www.facebook.com\/kuzeyinsesii","article_published_time":"2026-09-18T00:47:03+00:00","og_image":[{"url":"https:\/\/trthaberstatic.cdn.wp.trt.com.tr\/resimler\/2096000\/fare-reu-2096338.jpg","type":"","width":"","height":""}],"author":"Kuzeyin Sesi","twitter_card":"summary_large_image","twitter_creator":"@kuzeyinsesii","twitter_site":"@kuzeyinsesii","twitter_misc":{"Yazan:":"Kuzeyin Sesi","Tahmini okuma s\u00fcresi":"3 dakika"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/kuzeyinsesi.org\/index.php\/2026\/09\/18\/bilimsel-bir-atilimla-yari-insan-yari-fare-beyin-gelistirildi\/#article","isPartOf":{"@id":"https:\/\/kuzeyinsesi.org\/index.php\/2026\/09\/18\/bilimsel-bir-atilimla-yari-insan-yari-fare-beyin-gelistirildi\/"},"author":{"name":"Kuzeyin Sesi","@id":"https:\/\/kuzeyinsesi.org\/#\/schema\/person\/9f859689cdf01485597712386e37f5aa"},"headline":"Bilimsel bir at\u0131l\u0131mla yar\u0131 insan yar\u0131 fare beyin geli\u015ftirildi","datePublished":"2026-09-18T00:47:03+00:00","mainEntityOfPage":{"@id":"https:\/\/kuzeyinsesi.org\/index.php\/2026\/09\/18\/bilimsel-bir-atilimla-yari-insan-yari-fare-beyin-gelistirildi\/"},"wordCount":625,"commentCount":0,"image":{"@id":"https:\/\/kuzeyinsesi.org\/index.php\/2026\/09\/18\/bilimsel-bir-atilimla-yari-insan-yari-fare-beyin-gelistirildi\/#primaryimage"},"thumbnailUrl":"https:\/\/kuzeyinsesi.org\/wp-content\/uploads\/2026\/09\/fare-reu-2096338.jpg","articleSection":["D\u00fcnya"],"inLanguage":"tr","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/kuzeyinsesi.org\/index.php\/2026\/09\/18\/bilimsel-bir-atilimla-yari-insan-yari-fare-beyin-gelistirildi\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/kuzeyinsesi.org\/index.php\/2026\/09\/18\/bilimsel-bir-atilimla-yari-insan-yari-fare-beyin-gelistirildi\/","url":"https:\/\/kuzeyinsesi.org\/index.php\/2026\/09\/18\/bilimsel-bir-atilimla-yari-insan-yari-fare-beyin-gelistirildi\/","name":"Bilimsel bir at\u0131l\u0131mla yar\u0131 insan yar\u0131 fare beyin geli\u015ftirildi - 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